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00 pm Watershed
PM or pm (also written P.M. or p.m.) is an abbreviation for Latin ''post meridiem'', meaning "after midday" in the 12-hour clock. PM or Pm or pm may also refer to: Arts and entertainment *Palm mute, a guitar playing technique * ''PM'' (radio program), Australia * ''PM'' (BBC Radio 4), UK *''PM Magazine'', an American TV news program (1976–1991). * ''PM'' (newspaper), US (1940–1948) *PM Press, an American publishing company *'' Pocket Mortys'', a role-playing video game * Project Mayhem, a fictional conspiracy in the book and film ''Fight Club'' * PM, a band with drummer Carl Palmer. Business and economics Businesses * P.M. Place Stores, a former US chain of discount stores *Pere Marquette Railway, North America 1900–1947, reporting mark *Philip Morris International, a tobacco company Terminology *Performance management of an organisation *Portfolio manager *Preventive maintenance *Project manager *Product manager *Program manager * Product marketer Government *Prime mini ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
12-hour Clock
The 12-hour clock is a time convention in which the 24 hours of the day are divided into two periods: a.m. (from Latin , translating to "before midday") and p.m. (from Latin , translating to "after midday"). Each period consists of 12 hours numbered: 12 (acting as 0), 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, and 11. The 12-hour clock has been developed since the second millennium BC and reached its modern form in the 16th century. The 12-hour time convention is common in several English-speaking nations and former British Empire, British colonies, as well as a few other countries. In English-speaking countries: "12 p.m." usually indicates noon, while "12 a.m." means midnight, but the reverse convention has also been used (see #Confusion at noon and midnight, § Confusion at noon and midnight). "Noon" and "midnight" are unambiguous. History and use The natural day-and-night division of a calendar day forms the fundamental basis as to why each day is split ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Program Manager
Program Manager is the shell of Windows 3.x and Windows NT 3.x operating systems. This shell exposed a task-oriented graphical user interface (GUI), consisting of ''icons'' ( shortcuts for programs) arranged into ''program groups''. It replaced MS-DOS Executive, a file manager, as the default Windows shell. OS/2 2.0 and later included the Program Manager as part of its Win-OS/2 compatibility layer. Win-OS/2, including the Program Manager, are still included in later derivatives of OS/2 such as ArcaOS. Overview Program Manager descends from ''Desktop Manager'' (also known as Presentation Manager), the shell for OS/2 1.2. Unlike Desktop Manager, which presents its program groups in a simple list, and opens each group in a separate window, Program Manager opens program groups in child windows using the new multiple document interface in Windows 3.x. The icons used to represent Program Manager itself, program groups, and DOS applications in Windows 3.0 are carried over from OS/2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PM3 (chemistry)
PM3, or Parametric Method 3, is a semi-empirical method for the quantum calculation of molecular electronic structure in computational chemistry. It is based on the Neglect of Differential Diatomic Overlap integral approximation. The PM3 method uses the same formalism and equations as the AM1 method. The only differences are: 1) PM3 uses two Gaussian functions for the core repulsion function, instead of the variable number used by AM1 (which uses between one and four Gaussians per element); 2) the numerical values of the parameters are different. The other differences lie in the philosophy and methodology used during the parameterization: whereas AM1 takes some of the parameter values from spectroscopical measurements, PM3 treats them as optimizable values. The method was developed by J. J. P. Stewart and first published in 1989. It is implemented in the MOPAC program (of which the older versions are public domain), along with the related RM1, AM1, MNDO and MINDO meth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pyridoxamine
Pyridoxamine (PM) is one form of vitamin B6. Chemically it is based on a pyridine ring structure, with hydroxyl, methyl, aminomethyl, and hydroxymethyl substituents. It differs from pyridoxine by the substituent at the 4-position. The hydroxyl at position 3 and aminomethyl group at position 4 of its ring endow pyridoxamine with a variety of chemical properties, including the scavenging of free radical species and carbonyl species formed in sugar and lipid degradation and chelation of metal ions that catalyze Amadori reactions. Research Pyridoxamine can form fairly weak complexes with a number of transition metal ions, with a preference for Cu2+ and Fe3+. The 3'-hydroxyl group of pyridoxamine allows for efficient hydroxyl radical scavenging. Pyridoxamine inhibits the Maillard reaction and can block the formation of advanced glycation endproducts, which are associated with medical complications of diabetes. Pyridoxamine is hypothesized to trap intermediates in the forma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Precision Medicine
Precision, precise or precisely may refer to: Arts and media * ''Precision'' (march), the official marching music of the Royal Military College of Canada * "Precision" (song), by Big Sean * ''Precisely'' (sketch), a dramatic sketch by the English playwright Harold Pinter Science, and technology, and mathematics Mathematics and computing (general) * Accuracy and precision, measurement deviation from true value and its scatter * Significant figures, the number of digits that carry real information about a measurement * Precision and recall, in information retrieval: the proportion of relevant documents returned * Precision (computer science), a measure of the detail in which a quantity is expressed * Precision (statistics), a model parameter or a quantification of precision Computing products * Dell Precision, a line of Dell workstations * Precision Architecture, former name for PA-RISC Precision Architecture reduced instruction set computer, RISC (PA-RISC) or Hewlet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Post-mortem
An autopsy (also referred to as post-mortem examination, obduction, necropsy, or autopsia cadaverum) is a surgical procedure that consists of a thorough examination of a corpse by dissection to determine the cause, mode, and manner of death; or the exam may be performed to evaluate any disease or injury that may be present for research or educational purposes. The term ''necropsy'' is generally used for non-human animals. Autopsies are usually performed by a specialized medical doctor called a pathology, pathologist. Only a small portion of deaths require an autopsy to be performed, under certain circumstances. In most cases, a medical examiner or coroner can determine the cause of death. Purposes of performance Autopsies are performed for either legal or medical purposes. Autopsies can be performed when any of the following information is desired: * Manner of death must be determined ** Determine if death was natural or unnatural ** Injury source and extent on the corpse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Poor Metabolizer
Pharmacogenomics, often abbreviated "PGx," is the study of the role of the genome in drug response. Its name ('' pharmaco-'' + ''genomics'') reflects its combining of pharmacology and genomics. Pharmacogenomics analyzes how the genetic makeup of a patient affects their response to drugs. It deals with the influence of acquired and inherited genetic variation on drug response, by correlating DNA mutations (including point mutations, copy number variations, and structural variations) with pharmacokinetic (drug absorption, distribution, metabolism, and elimination), pharmacodynamic (effects mediated through a drug's biological targets), and/or immunogenic endpoints. Pharmacogenomics aims to develop rational means to optimize drug therapy, with regard to the patients' genotype, to achieve maximum efficiency with minimal adverse effects. It is hoped that by using pharmacogenomics, pharmaceutical drug treatments can deviate from what is dubbed as the "one-dose-fits-all" appro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polymyositis
Polymyositis (PM) is a type of chronic inflammation of the muscles ( inflammatory myopathy) related to dermatomyositis and inclusion body myositis. Its name is derived . The inflammation of polymyositis is mainly found in the endomysial layer of skeletal muscle, whereas dermatomyositis is characterized primarily by inflammation of the perimysial layer of skeletal muscles. Signs and symptoms The hallmark of polymyositis is weakness and/or loss of muscle mass in the proximal musculature, as well as flexion of the neck and torso. These symptoms can be associated with marked pain in these areas as well. The hip extensors are often severely affected, leading to particular difficulty in climbing stairs and rising from a seated position. The skin involvement of dermatomyositis is absent in polymyositis. Dysphagia (difficulty swallowing) or other problems with esophageal motility occur in as many as 1/3 of patients. Low grade fever and enlarged lymph nodes may be present. Foot dro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasma Membrane
The cell membrane (also known as the plasma membrane or cytoplasmic membrane, and historically referred to as the plasmalemma) is a biological membrane that separates and protects the interior of a cell from the outside environment (the extracellular space). The cell membrane consists of a lipid bilayer, made up of two layers of phospholipids with cholesterols (a lipid component) interspersed between them, maintaining appropriate membrane fluidity at various temperatures. The membrane also contains membrane proteins, including integral proteins that span the membrane and serve as membrane transporters, and peripheral proteins that loosely attach to the outer (peripheral) side of the cell membrane, acting as enzymes to facilitate interaction with the cell's environment. Glycolipids embedded in the outer lipid layer serve a similar purpose. The cell membrane controls the movement of substances in and out of a cell, being selectively permeable to ions and organic molecu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pat Maloney Sr
Pat or PAT may refer to: Arts, entertainment and media Fictional characters * Pat (''Alice's Adventures in Wonderland''), a gardener * Pat (''Saturday Night Live''), an androgynous character * Postman Pat, a British children's TV character * Pat, from the Czech series '' Pat & Mat'' * Pat the Dog, a character from the TV show of the same name * Pat, or Lucky's Dad, a ''Bluey'' character * Pat, daughter-in-law of Jake the Dog in ''Adventure Time'' Other uses in arts, entertainment and media * ''"Pat"'' (album), by Pat Boone, 1957 * , in Bolivia Businesses and organisations * Pakistan Awami Tehreek, a political party * Polish Telegraphic Agency, the official news agency of Poland 1918–1991 * Port Authority of Thailand * Professional Association of Teachers, later Voice, a former British trade union * PAT (), a type of Ukrainian legal entity, equivalent to plc People * Patrick (given name), including a list of people with the name, sometimes known as Pat * Patricia, a fe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hans Widmer
''bolo'bolo'' is a 1983 book by P.M., a pseudonym for Hans Widmer, in which he outlines a plan for utopia. Synopsis The opening of ''bolo'bolo'' describes and criticizes the current world, called the Planetary Work Machine, which the work describes as based on domination and has resulted in the despoiling of the natural world. He describes the Machine as decentrally orchestrated by corporations and government (and their representatives) who each independently increase their control over others, quashing resistance and the viability of alternative systems. He advocated the undermining of the system via subversion and construction ("substruction"). It then presents a plan and a future history in which humanity transitions into the ''bolo'' system. The remainder of the work describes the theoretical future social order and defines terms. A "bolo" is an intentional community formed of about 500 "ibus", or individual egos. The intentional community is described through its lifes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bureau Of Political-Military Affairs
The Bureau of Political-Military Affairs (PM) is an agency within the United States Department of State that bridges the Department of State with the Department of Defense. It provides policy in the areas of international security, security assistance, military operations, defense strategy and policy, military use of space, and defense trade. It is headed by the Assistant Secretary of State for Political-Military Affairs. Function According to the Department of State website, the Bureau secures military base access and overflight permission to support the deployment of U.S. military forces. It negotiates the status of U.S. military forces and International Criminal Court non-surrender agreements. It is also responsible for coordinating the participation of coalition combat and stabilization forces, and assisting other countries in reducing the availability of man-portable air defense systems (MANPADS), which are shoulder-launched surface-to-air missiles. The Bureau seeks to cr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
